小發(fā)夾RNA（英語：short hairpin RNA，縮寫shRNA）是一種形成急轉(zhuǎn)彎（hairpin turn）結(jié)構(gòu)的RNA序列，可以經(jīng)由RNA干擾（RNAi）使基因表現(xiàn)沉默化。shRNA可利用載體導(dǎo)入細(xì)胞當(dāng)中，并借由U6啟動子來確保shRNA的表現(xiàn)。另外，shRNA可經(jīng)由切割轉(zhuǎn)變成為siRNA
參考文獻(xiàn)
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